2009 Harry Hirsch Leiter Award Recipient: Epidemiology of ulcerative keratitis in northern California

• B.H..Jeng,^1,2, D.C. Gritz ^1,2 , A.B. Kumar¹, D.S. Holsclaw^1,4 , T.C. Porco^1,5 , S.D. Smith² , J.P. Whitcher¹ , T.P. Margolis¹ , I.G. Wong^{1,6
  1}F.I. Proctor Foundation and the Department of Ophthalmology, University of California, San Francisco, CA., ² Cole Eye Institute, Cleveland Clinic, Cleveland, OH.,³ Kaiser Permanente Foundation Hospitals-Oakland, Richmond, CA, ⁴ Redwood City, CA, ⁵ Dept. of Epidemiology and Biostatistics, University     of California, San Francisco, CA, ⁶Dept. of Ophthalmology, Stanford Univ., Palo Alto, CA

Epidemiology of ulcerative keratitis in northern California

• B.H. Jeng^1,2, D.C. Gritz^1,3, A.B. Kumar¹, D.S. Holsclaw^1,4, T.C. Porco^1,5, S.D. Smith², J.P. Whitcher¹, T.P. Margolis¹, I.G. Wong^{1,6
  1}F.I. Proctor Foundation and the Dept. of Ophthalmology, Univ. of CA San Francisco, ²Cole Eye Institute, Cleveland Clinic, OH, ³Kaiser Permanente Foundation Hospitals-Oakland, Richmond, and ⁴Redwood City, CA, ⁵Dept. of Epi. and Biostatistics, Univ. of CA San Francisco, ⁶Dept. of Ophthalmology, Stanford Univ., Palo Alto, CA

Diagnosis of Microsporidial Keratitis by Polymerase Chain Reaction.

• G.A.K. Reddy¹, P.K. Balne¹, K. Gaje¹, P. Garg^{2
  1}Jhaveri Microbiology Centre, Hyderabad Eye Research Foundation, L.V. Prasad Eye Institute, Hyderabad, India,
  ²Cornea and Anterior Segment Services, L.V. Prasad Eye Institute, Hyderabad, India.

A 12-year Retrospective PCR Testing Study of Ocular Specimens for Chlamydia, HSV, Adenovirus, and VZV.

• R.P. Kowalski, P.P. Thompson,
  Charles T. Campbell Ophthalmic Microbiology Laboratory,
  University of Pittsburgh, Pittsburgh, PA, USA

Improper Storage / Transport Temperatures, Defective Plastic Bottles, and the Worldwide Fusarium Keratitis Epidemic of 2004-2006.

• J.D. Bullock, L. Elder, R.E. Warwar
  Departments of Community Health, Mathematics and Statistics, Ophthalmology, and Pathology, Wright State University Boonshoft School of Medicine, Dayton, OH

Multidrug Resistant Fusarium Keratitis Progressing to Endophthalmitis.

• S.L. Edelstein, H. Hsu, L. Akduman
  St. Louis University Eye Institute, St. Louis University, St. Louis, MO

In Vivo Confocal Microscopy of Corneal Nerve Alterations in Acute Acanthamoeba and Fungal Keratitis.

• K. Kurbanyan, L.M. Hoesl, W.A. Schrems, P. Hamrah.
  Cornea Service & Ocular Surface Imaging Center, Massachusetts Eye and Ear Infirmary, Harvard  Medical School, Boston, MA.

Acanthamoeba Endophthalmitis following Penetrating Keratoplasty for Acanthamoeba Keratitis.

• M.J. Davis^1,2, K.H. Packo1,², R.J. Epstein1,³, R.J. Grostern¹, J.A. Cohen^{1,2
  1} Rush University Medical Center, Department of Ophthalmology , Chicago IL. ² Illinois Retina Associates, Chicago, IL. ³ Chicago Cornea Consultants, Chicago, IL

Resolution of acanthamoeba keratoconjuncitivitis without the use of anti-acanthamoebal therapy.

• L.J. Cervantes, C.Y. Shih, D.C. Ritterband, M Shah,
  J.A. Seedor, I.J. Udell
  North Shore/Long Island Jewish Health System;
  New York Eye and Ear Infirmary

Partial characterization of collagenolytic enzymes secreted by Acanthamoeba virulent strains.

• F.R.S. Carvalho¹, L.C. Carrijo-Carvalho², A.M. Chudzinski-Tavassi²,A.S. Foronda¹, D de Freitas^{1
  1}Federal University of Sao Paulo, Department of Ophthalmology;
  ²Butantan Institute, Laboratory of Biochemistry and Biophysics.

Bacterial Transference by Needles Passed through Cadaveric Conjunctiva.

• M. Mifflin, J. Pettey, W. McEntire, D. Pettey, K. Kamae, Y.F. Khalifa,
  R.J. Olson
  University of Utah Department of Ophthalmology, Moran Eye Center, Salt Lake City, UT

The effect of bacterial proliferation to lens capsule.

• S. Kobayakawa, T. Tochikubo.
  Department of Ophthalmology, Toho U., Tokyo, Japan. Tokyo, Japan.

Persistence of MRSA on Ocular Surface following Primary Infection.

• D. Miller¹, D. Almeida², E. Alfonso¹
  Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida¹, Department of Ophthalmology, Queen’s University, Kingston, Ontario²

Prophylactic Treatment of Staphylococcus aureus Infection in the Rabbit Anterior Chamber with Vigamox or Besivance.

• C.L. Balzli, A. Caballer, A. Tang, C.C. McCormick, R.J. O’Callaghan
  Department of Microbiology, University of Mississippi Medical Center, Jackson, MS

The Evaluation of Levofloxacin 1.5% in the Treatment of Levofloxacin-Susceptible and Resistant Staphylococcus aureus and Pseudomonas aeruginosa in Rabbit Keratitis Models.

• E.G. Romanowski, R.P. Kowalski, F.S. Mah,
  R.M.Q. Shanks, Y.J. Gordon
  The Charles T. Campbell Ophthalmic Microbiology Laboratory, UPMC Eye Center, Ophthalmology and Visual Sciences Research Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Inhibition of Staphylococcal Biofilm Formation in vitro by DuraSite and AzaSite.

• E. Wu, F.S. Mah, E.G. Romanowski, R.P. Kowalski, Y.J. Gordon,
  and R.M.Q. Shanks
  The Charles T. Campbell Laboratory, UPMC Eye Center, Ophthalmology and Visual Sciences Research Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA

American and Indian clinical isolates of P. aeruginosa harbor CRISPR genes from multiple subtypes.

• J.H. Hammond¹, K.C. Cady¹, P Lalitha³, R..S. Karthikeyan³ , R.T. Allar², G.A. O’Toole¹,  M. E. Zegans^{1,2
  1}Dept of Microbiology and Immunology,
  ²Dept of Surgery (Ophthalmology) Dartmouth Medical School, Hanover, NH,
  ³Dept of Ocular Microbiology, Aravind Eye Hospital, Madurai, India

Muckle-Wells Syndrome: Ophthalmic Findings in Seven Patients.

• J.M. Schrieber¹, N.P. Barney^1,2
  University of Wisconsin School of Medicine and Public Health¹,
  Madison, WI, Dept. of Ophthalmology and Visual Sciences²

Itchy Eyes. Really Itchy Eyes: Poison Ivy Keratitis.

• S.L. Williamson, R.S. Weinberg
  Johns Hopkins University School of Medicine, Wilmer Eye Institute, and Johns Hopkins Bayview Medical Center, Baltimore, MD  

Mannose Binding Lectin as part of the Complement System: Absent in the Normal Eye but Present in the Inflamed Human Eye.

• S. Chow¹, M. Daniell¹, M. Dean³, J. Depla⁴, D. Eisen^{2
  1}Department of Ophthalmology, Royal Melbourne Hospital, Melbourne Australia,  ²Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, Australia, ³Co-operative Research Centre for Vaccine Technology, Brisbane, Australia, ⁴Vitreo-retinal Unit, Royal Victorian Eye and Ear Hospital, Melbourne, Australia

Blockade of Vascular Endothelial Growth Factor-C (VEGF-C) Suppresses Blood (Heme-) and Lymph-angiogenesis and Improves Corneal Transplant Survival.

• A.R. Hajrasouliha, T Funaki, Z Sadrai, T Hattori, R Dana
  Schepens Eye Research Institute, Harvard Medical School, Boston, MA.

Therapeutic Eefficacy of Topical Blockade of Interleukin-1 in Murine Dry Eye Disease.

• A. Okanobo, M. Dastjerdi, S. Chauhan, N. Nallasamy, Z. Sadrai, R. Dana
  Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary, Harvard Medical School,  Boston,  Massachusetts  

A Combination Povidone-Iodine 0.4% / Dexamethasone 0.1% Ophthalmic Suspension in the Treatment Of Adenoviral Conjunctivitis.

• J.S. Pelletier¹, K. Stewart¹, W. Trattler², D.C. Ritterband^3,4, S. Braverman⁵, C.M. Samson^3,4,6, B. Liang⁶, J.A. Capriotti^{1,6
  1} Ocean Ophthalmology Group, North Miami Beach, FL,  ²The Center For Excellence in Eye Care, Miami, FL, ³New York Eye and Ear Infirmary, New York, NY, ⁴New York Medical College, Valhalla, NY, ⁵Braverman Eye Center, Hallandale Beach, FL, ⁶CLS Pharmaceuticals, New York, NY

10:34 am

Human Adenovirus Type D53: Molecular Evolution Influencing Tropism.

• J. Chodosh ¹, M.P. Walsh², A.V. Chintakuntlawar¹, C.M. Robinson¹, I. Madisch³, B. Harrach⁴, N.R. Hudson⁵, D. Schnurr⁶, A. Heim³, D. Seto², M.S. Jones^{5
  1}Mass. Eye and Ear Infirmary – Harvard Medical School, ²George Mason University, ³Insitut für Virologie – Medizinische Hochschule, ⁴Veterinary Med. Res. Inst. - Hungarian Academy of Sciences,  ⁵David Grant USAF Medical Center – Travis AFB, ⁶Viral and Rickettsial Disease Laboratory – California Dept of Public Health

2008 Harry Hirsch Leiter Award Recipient:
Endosymbionts as co-pathogens in Acanthamoeba keratitis.

• A. Iovieno^l,2, D. Miller¹, D. Ledee¹, N. Mandal¹, E. Alfonso^{1
  1}Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine,Miami, FL;
  ²Ophthalmology Department, University Campus Bio-medico, Rome, Italy.

14th Thygeson Lecture:
Establishment of Latent infection with Herpes Simplex Virus.

• Todd P. Margolis, M.D., Ph.D., Professor of Ophthalmology, Rose B. Williams Chair in Corneal Research and Director, Francis I. Proctor Foundation

Closing Comments and Awards

12:00 pm